Light, D.W. and Lexchin, J.R. “The costs of coronavirus vaccines and their pricing.” Journal of the Royal Society of Medicine 2021 Vol 114 (11): 502-504.
The net cost for researching, testing and manufacuturing Western vaccines, after subtracting all public subsidies, is much smaller that what the US and Europe are agreeing to pay for them. This makes them unaffordable to many middle and lower income countries and impedes treating the global pandemic.
Darrow, Jonathan and Donald Light, “Beyond The High Prices Of Prescription Drugs: A Framework To Assess Costs, Resource Allocation, And Public Funding,” Health Affairs 2021, vol. 40, No. 2:281-88.
Corporate R&D costs for new drugs in the U.S. are reduced by a large number of taxpayer-paid subsidies. They are further reduced by "pull" subsidies built into patents and insurance. This article pulls these subsidies into a comprehensive framework for tracking and accounting for public subsidies for pharmaceutical corporate R&D.
Light, D.W. and Lexchin, J.R. 2021 “Pharmaceuticals as a market for ‘lemons’: theory and practice.” Social Science and Medicine 268 113368
This overview first considers and revises the economic theory of 'lemons', that is products like cars and drugs in which sellers know about hidden flaws and risks of harm but do not disclose them to buyers. The authors then describe how incentives and institutional practices reward companies for producing more 'lemons'. The market for more drugs with hidden risks and flaws is likely to flourish.
2. "Why do cancer drugs get such an easy ride? Many trials allowed that lack basic features for clear evidence of benefits or harms.
3. "Serious risks for few new benefits from FDA-approved drugs" That's what the FDA gives us.
Pulls together the syndrome of practices, laws, and rules that are maximizing harmful side effects from new drugs that usually provide few or no off-setting benefits.
Presents evidence of an epidemic of adverse reactions that have made prescription drugs the 4th leading cause of death, tied with stroke. A major cause of hospitalizations, falls, and accidents.
The more drugs are marketed, the more diluted become their benefits but the more widespread become their harmful side effects.
Review of Deadly Medicines And Organised Crime: How Big Pharma Has Corrupted Healthcare By Peter C. Gøtzsche
PHARMAMYTHS AND REALITIES
The quality of the data, however, is terrible; so who knows what the real story is? Yet major policies are decided on this terrible data and bias analysis.
GLOBAL JUSTICE AND VACCINES FOR THE POOR